Allergies and autoimmunity are two major factors that cause autoimmune diseases. Your body’s immune system guards you against infection and illness. However, sometimes your body attacks healthy cells by mistake. Autoimmune diseases can attack many parts of your body. Some of these diseases include psoriasis, Lupus, multiple sclerosis, acne, meningitis, septic arthritis, etc.
Play A Role In Inflammatory Diseases
Researchers have found that antibodies may play a role in inflammatory diseases. However, they were not able to confirm the hygiene hypothesis. It is believed that the immune response to infection and illness damages healthy tissues. However, the immunity response may not always destroy all foreign antigens. This leads to the destruction of some good tissues as well as the growth of new inflammatory T-cells.
Scientists have discovered certain cases where autoimmune diseases have a genetic component. There are also cases when the disorder has an environmental component. The environmental factors that trigger the disorders vary from case to case.
Some of the autoimmune diseases have a common characteristic: they involve the immune response to infections and illness. In allergies, the antibodies affect the protective myelin sheath around the lungs and other organs. In autoimmune diseases, the antibodies affect the myelin sheath in the brain. Abnormal antibodies in the blood can injure normal myelin sheath in the brain. This leads to destruction of synapses.
The symptoms vary from one autoimmune disease to another. Some of these diseases include septic arthritis, Lupus, skin problems, acne, meningitis, etc. The symptoms of certain diseases do not occur. This is the result of various theories about how the immune response works.
Providing Oxygen To The Knee
The blood vessels in the knee are important for providing oxygen to the knee. If the blood vessels are damaged due to autoimmune diseases, the persons may experience excruciating knee joint pain. Knee joint pain is usually a symptom of a systemic autoimmune diseases and if this happens, the persons may experience headaches, loss of vision and hearing, etc.
Other autoimmune diseases have a weak or non-specific effect on immunity. One example is the increased risk of developing invasive breast cancer in women with coeliac disease. Women with coeliac disease have a lower tolerance to gluten and therefore are at a higher risk for developing invasive breast cancer. Coeliac disease is an autoimmune disease in which the body attacks its own tissues due to its intolerance to gluten. Therefore, gluten intolerance is a cause of several autoimmune diseases.
Studies on autoimmune diseases have indicated that genetic disorders can lead to the development of inflammatory diseases and chronic illnesses that co-occur with the other. Examples of these genetic disorders include cystic fibrosis, sickle cell anemia and migraine headaches. In most of these patients, the symptoms developed years after the onset of the disease. Another common indicator for the development of autoimmune diseases is the abnormal localization of white blood cells within the blood. These white blood cells are part of the body’s defense mechanism against infectious agents but when they recognize unhealthy cells as foreign, they trigger an exaggerated immune response which results in chronic inflammation and the production of autoantibodies, damaging the healthy cells.